![Pinterest](https://pinterest.com/pin/create/button/?url=https://uknews.evprotec.com/major-breakthrough-for-millions-with-silent-killer-as-worlds-first-jab-could-replace-daily-drugs/&media=https://uknews.evprotec.com/wp-content/uploads/2023/07/file-photo-dated-10-09-832460355.jpg&description=GAME CHANGER Major breakthrough for millions with 'silent killer' as world's first jab could replace daily drugs A MAJOR breakthrough has been made for millions of people with high blood pressure - as the world's first jab could replace daily drugs. British medics have been trialling a world-first injection to control the "silent killer" condition, which is a leading cause of strokes and heart attacks. 2 British medics have been leading a trial into a new twice-yearly injection Credit: PA Millions of Brits currently take daily pills to keep their blood pressure in order. But experts at Queen Mary University of London have been carrying out a trial involving an injection that is given every six months. The medication, known as Zilebesiran and made by US-based Alnylam Pharmaceuticals, works by targeting a key hormone produced by the liver. Researchers recruited 107 patients with hypertension, of whom 80 were given an injection of zilebesiran under their skin and 32 received a placebo with no active ingredients. Five of the 32 patients who received the placebo were later given zilebesiran. Initial analysis shows that volunteers who were given zilebesiran experienced a significant drop in systolic blood pressure which lasted up to six months, MailOnline reports. Systolic blood pressure, namely the pressure in your arteries when your heart beats, lowered by more than 10mmHg at least a 200mg dose and 20mmHg at the highest of 800mg. The drop can take a patient's high blood pressure into a safer range. High blood pressure is the biggest single trigger of heart disease and stroke. It is known as the silent killer, because the symptoms often go unnoticed until it is too late. Under NHS rules, it is a reading over 140/90mmHg – with around 12 million people eligible for treatment. Despite high blood pressure being difficult to treat due to its fluctuations across a day, the zilebesiran medication resulted in a consistent drop over 24 hours. Zilebesiran prevents the production o){kind=link}
A MAJOR breakthrough has been made for millions of people with high blood pressure – as the world’s first jab could replace daily drugs.
British medics have been trialling a world-first injection to control the “silent killer” condition, which is a leading cause of strokes and heart attacks.
Millions of Brits currently take daily pills to keep their blood pressure in order.
But experts at Queen Mary University of London have been carrying out a trial involving an injection that is given every six months.
The medication, known as Zilebesiran and made by US-based Alnylam Pharmaceuticals, works by targeting a key hormone produced by the liver.